Hemoprotein

What is Hemoprotein

Structure of Hemoprotein

What is porphyrins included in Heme biosynthesis

Formation of Heme ( all steps )

The site of Heme formation

Key regulatory enzyme in Heme biosynthesis

Distribution of side chain in porphyrins

Different between porphyrins & porphyrinogen

Effect of drug on ALA synthase

Porphyrias definition, types, clinical manifestation, treatment

Degradation of Heme , the occurrence site

Different between bilirubin & biliverdin

UDP & its role in Heme degradation

The only reaction in the body produce monoxide

Daily bilirubin formation

Distinguished between urobilinogen, urobilin, urochrom

Jaundice definition, causes, types, effects

Classification of HYPERBILIRUBINEMIA

Comparison between direct indirect bilirubin

Urobilinogen, bilirubin in urine are important clinical indicators

Gene Expression

What is Gene Expression

What is Gene ?

Active chromatin & non active chromatin

The Differences between prokaryotic & eukaryotic of genetic information

DNA structure & organization

Central Dogma

Cell cycle

Major features of structure & function of human Mt DNA

Comparison between eukaryotes & prokaryotes

Regulation of eukaryotic gene expression intracellular & intercellular signals ( HREs,  SRE)

 

DNA REPLICATION

 

Mechanism ( all steps initiation, elongation, termination )

Comparison between prokaryotic & eukaryotic

Proteins involved in DNA replication

Enzymes involved in DNA replication require ATP

Types of DNA polymerases ( comparison between those in eukaryotes & prokaryotes)

supercoiling & its repairing enzyme which enzyme require ATP involved in DNA replication

reverse transcriptase

replication bubble replication fork

comparison between leading & lagging strand

mechanism of action of primase, telomerase

comparison between eukaryotic & prokaryotic DNA polymerase

( comparison in each one )

drugs , analogs  affecting  replication

DNA repair ( definition, mechanism, types & subtypes )

 

TRANSCRIPTION ( RNA synthesis )

 

Requirements , types of RNA

Types of promoter ( in both prokaryotic & eukaryotes )

RNA polymerase ( only one type in prokaryotic & 3 types in eukaryotic)

Mechanism  ( all steps initiation, elongation, termination in both eukaryotic & prokaryotic )

Requirement of mRNA synthesis in eukaryotes

RNA polymerase II inhibited  by a- Amanitin treated by active carbon

Comparison between rRNA in both prokaryotic & eukaryotic

Inhibitors of transcription

RNA synthesis modification ( post-transcriptional modification)

Enhancers ( differs from promoter ,  has important role in Transcription )

 

 

 

TRANSLATION ( protein synthesis )

 

Requirements

Mechanism (All steps,  initiation,  elongation,  termination in both prokaryotes & eukaryotes)

Inhibitors of protein synthesis

Post-translational modification of polypeptide chain

TWO MAJOR ENZYME SYSTEM IN PROTEIN DEGRADATION

( protease, lysosome )

MUTATION ( definition, causes, types & subtypes )

 

 

Clinical Cases – Biochemistry 2016 sem3

Biochemistry Clinical Cases records by Dr.unknown

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Biochemistry Clinical Enzymology – Dr M.Annajjar sem3

Biochemistry Clinical Enzymology records by Dr.M.Annajjar

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Recombinant & PCR -Dr Abdulla Bashein 2016 sem3

Biochemistry Regulation of Gene Expression records by Dr.Abdulla Bashein

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Regulation of Gene Expression 2016 Dr Abdulla Bashein sem3

Biochemistry Regulation of Gene Expression records by Dr.Abdulla Bashein

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Biochemistry Gene Expression 2016 Dr Ahmed Zaid sem3

Biochemistry Gene Expression records by Dr.Ahmed Zaid

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