What is pharmacodynamics
Mode of action of drug
Properties of action selectivity, affinity, structure activity relationship, chirality
Classification of receptor
Different between enzyme incorporated receptor & cytokine receptor
Types of intracellular second messenger
Types of drug response
What is potency, efficacy & it is related to drug action
Clinical important of IT
Causes increase responsiveness & causes reduce responsiveness ( tolerance)
Types of tolerance
Different between desensitization & hypersensitivity
Comparison between agonist & antagonist
Types of agonist
Types of antagonist
Factors modifying drug action
What is the pharmacology, PK ,PD
What is the different between pharmacotherapeutics & toxicology branch of pharmacology
When should be describe ( tablets, enema, drops or gels)
Comparison between routes of drug intake
The relationship between routes of drug intake & health status of patient
Some drugs have ( local \ systemic effects) some are given ( limited dose \ small amount)
What is bioavailability?
The relationship between routes & bioavailability of drugs
Absorption of drug
Comparison between active & passive transfer
The different between filtration & simple diffusion
The different between facilitated diffusion & active transport
Factors affect absorption of drug
Volume of Distribution & its related to plasma protein binding ( AGP, albumin, lipoprotein)
Factors affecting distribution of drug
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